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Center for Medical Statistics, Informatics and Intelligent Systems
Artificial Intelligence Institute
A translational data integration platform for the stratification of patients based on clinical, laboratory and magnetic resonances imaging data.
CLUSTER aims to bring together knowledge from internationally recognised leaders to create biomarker tests to predict disease outcomes for childhood arthritis.
New clinical endpoints in primary Sjögren’s syndrome: an interventional trial based on stratifying patients.
BioCog will establish valid biomarkers panels for risk and clinical outcome prediction of POD/POCD (Postoperative Delirium/Postoperative Cognitive Dysfunction).
Delivering European Translational Information & Knowledge Management Services.
Organising mechanistic knowledge about neurodegenerative diseases for the improvement of drug development and therapy.
A data science approach for the identification of molecular signatures of aggressive cancers (https://zenodo.org/record/6368086#.Yois6OhByS4).
Machine learning analysis of NCBI GSE studies for epigenomics. (https://zenodo.org/record/4291069#.YoisYehByS4)
Piereck B, Oliveira-Lima M, Benko-Iseppon AM, et al. LAITOR4HPC: A text mining pipeline based on HPC for building interaction networks. BMC Bioinformatics. 2020;21(1):365. Published 2020 Aug 24. doi:10.1186/s12859-020-03620-4
Barbosa-Silva A, Bratfalean D, Gu W, et al. Presenting and sharing clinical data using the eTRIKS Standards Master Tree for tranSMART. Bioinformatics. 2019;35(9):1562-1565. doi:10.1093/bioinformatics/bty809
Herzinger S, Gu W, Satagopam V, et al. SmartR: an open-source platform for interactive visual analytics for translational research data. Bioinformatics. 2017;33(14):2229-2231. doi:10.1093/bioinformatics/btx137
Wethmar K, Barbosa-Silva A, Andrade-Navarro MA, Leutz A. uORFdb--a comprehensive literature database on eukaryotic uORF biology. Nucleic Acids Res. 2014;42(Database issue):D60-D67. doi:10.1093/nar/gkt952
Soldatos TG, O'Donoghue SI, Satagopam VP, et al. Caipirini: using gene sets to rank literature. BioData Min. 2012;5(1):1. Published 2012 Feb 1. doi:10.1186/1756-0381-5-1
Barbosa-Silva A, Fontaine JF, Donnard ER, Stussi F, Ortega JM, Andrade-Navarro MA. PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries. BMC Bioinformatics. 2011;12:435. Published 2011 Nov 9. doi:10.1186/1471-2105-12-435
Fontaine JF, Priller F, Barbosa-Silva A, Andrade-Navarro MA. Génie: literature-based gene prioritization at multi genomic scale. Nucleic Acids Res. 2011;39(Web Server issue):W455-W461. doi:10.1093/nar/gkr246
Barbosa-Silva A, Soldatos TG, Magalhães IL, et al. LAITOR--Literature Assistant for Identification of Terms co-Occurrences and Relationships. BMC Bioinformatics. 2010;11:70. Published 2010 Feb 1. doi:10.1186/1471-2105-11-70
Soldatos TG, O'Donoghue SI, Satagopam VP, et al. Martini: using literature keywords to compare gene sets. Nucleic Acids Res. 2010;38(1):26-38. doi:10.1093/nar/gkp876
Fontaine JF, Barbosa-Silva A, Schaefer M, Huska MR, Muro EM, Andrade-Navarro MA. MedlineRanker: flexible ranking of biomedical literature. Nucleic Acids Res. 2009;37(Web Server issue):W141-W146. doi:10.1093/nar/gkp353
Barbosa-Silva A, Satagopam VP, Schneider R, Ortega JM. (SeedLinkage) Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence. BMC Bioinformatics. 2008;9:141. Published 2008 Mar 5. doi:10.1186/1471-2105-9-141
Barbosa-Silva A, Pafilis E, Ortega JM, Schneider R. Development of SRS.php, a Simple Object Access Protocol-based library for data acquisition from integrated biological databases. Genet Mol Res. 2007;6(4):1142-1150. Published 2007 Dec 11.
Cestari IS, Haver NJ, Barbosa-Silva A, Ramirez MI. PROTOGIM: a novel tool to search motifs and domains in hypothetical proteins of protozoan genomes. Parasitol Res. 2006;98(4):375-377. doi:10.1007/s00436-005-0064-0
My participation helped FIOCRUZ and QMUL to sign a memorandum of understanding for Scientific Collaboration.
Participation in the BRAGFOST'12 to develop science and technology interdisciplinary projects between Brazil and Germany. Held in the German Embassy in Brasilia.
Participation in the event: "Celebrating the 100,000 Genomes Project – a review and look ahead" held at the Royal Society in London (UK).
2022 (Recife/BR/Online) Oncogene 2020: Northeastern Seminar of Genetics
Organized by: UFPE/UFPI: https://www.instagram.com/oncogene.2022/
Speaker: Identification of Aggressiveness Signatures in Cancer using Data Science and Machine Learning
2022 (Salvador/BR/Online) I Summer course of Bioinformatics and Synthetic Biology
Organized by: CVBB: https://instagram.com/cvbb2022
Speaker: Bioinformatics Round Table
2021 (Recife/BR/Online) XI UFPE's Postgraduate in Genetics Programme Symposium
Organized by: UFPE: https://www.instagram.com/ppgg.ufpe
Speaker: One decade of text-mining analysis! Happy anniversary PESCADOR! What's next?
2020 (Rio de Janeiro/BR/Online) I Workshop On-line of Bioinformatics
Organized by: UFMG, https://ufmg.br/
Speaker: Bioinformatics Round Table
2020 (Rio de Janeiro/BR/Online) 1st international school on Big Data and Epigenomics applied to Public Health
Organized by: FIOCRUZ, https://portal.fiocruz.br/
Speaker: Transnational Data Integration for Translational Data Science.
2020 (London/UK/Online) London Bioinformatics e-talks series
Organized by: Imperial College London, https://www.imperial.ac.uk
Speaker: Machine learning for the stratification of Sjögren’s Syndrome patients using clinical and molecular data.
2020 (London/UK/Online) SMD COVID Research Seminar
Organized by: QMUL/SMD, https://www.qmul.ac.uk/smd/
Speaker: Comorbidities, Co-infections and COVID-19: systems biology approaches to find effective targets for antimicrobial peptides from Brazilian plants to fight the pandemic.
2020 (Brussels/BE) 4th Annual General Meeting - Final Open Meeting
Organized by: CORBEL, https://www.corbel-project.eu/
Speaker: Integrating EU-wide cardiovascular research datasets
2019 (Montevideo/UY) Personalised Medicine Technical Workshop
Organized by: EULAC, www.eulac-permed.eu
Speaker: Multimodal patient data integration to foster machine-learning aided personalized medicine
2019 (Heidelberg/DE) CORBEL Service Operator and User Meeting
Organized by: CORBEL, https://www.corbel-project.eu
2019 (London/UK) ELIXIR Bioinformatics Suppliers Forum 2019
Organized by: ELIXIR, https://elixir-europe.org/
Speaker: Clinical, OMICs and Imaging Data Integration
2017 (Barcelona/ES) BioTransR Meeting
Organized by: eTRIKS, http://etriks.org/
· Speaker: Data exploration using the eTRIKS/ tranSMART platform
2016 (San Diego/USA) The 2016 tranSMART Foundation Annual Meeting
Organized by: tranSMART Foundation, http://transmartfoundation.org/
· Speaker: Linking tranSMART to brain imaging, connectivity data and vis-tools
2016 (Barcelona/ES) NGS’16 – Next Generation Sequencing Meeting 2016
Organized by: ISCB, http://www.iscb.org
· Delegate
2015 (Luxembourg/LU) 3rd LCSB International Systems Biomedicine Symposium: Big data in Health Care
Organized by: University of Luxembourg http://www.uni.lu
· Delegate
2015 (Leuven/BE) EMBL Alumini Meeting
Organized by: EMBL Alumini Association, http://portal.fiocruz.br
· Speaker: UL Bioinformatics Core Approaches for Translational Bioinformatics
2014 (Rio de Janeiro/BR) International Course on Systems Biology Applied to Parasitology
Organized by: IOC/FIOCRUZ, http://portal.fiocruz.br
· Lecturer
2014 (Michigan/US) The 2014 tranSMART Foundation Annual Meeting
Organized by: tranSMART Foundation, http://transmartfoundation.org/
· Delegate
2014 (Boston/US) Intelligent Systems for Molecular Biology (ISMB)
Organized by: ISCB, http://www.iscb.org
· Delegate
2014 (Toronto/CAN) 7th International Biocuration Conference
Organized by OICR and ISB: http://biocuration2014.events.oicr.on.ca
· Eifes S, Barbosa-Silva A, Gu W, Satagopam VP, Schneider R (2014) Clinical cata curation in the framework of eTRIKS. In: Proceedings of the 7th International Biocuration Conference. Toronto, Canada.
2014 (Rio Grande do Norte/BR) Europe-Brazil Meeting on Systems and Synthetic Biology (2nd SB-Meeting)
Organized by UFRN and DKFZ: http://www.sb-meeting.com.br
· Speaker: Systems biology data integration to speed up the development of better and safer medicines for patients
· Chair: Symposium 2
2013 (Berlin/DE) Workshop on Molecular Interactions
Organized by: Univ. Potsdam, http://molecularinteractions.de
· Speaker: Text mining approaches to mine biological knowledge for systems biology
2013 (Berlin/DE) Intelligent Systems for Molecular Biology (ISMB)
Organized by: ISCB, http://www.iscb.org
· Delegate
2013 (Heidelberg/DE) International Conference on Systems Biology of Human Diseases (SBHD)
Organized by: DKFZ and Harvard Med. School, http://www.sbhd2013.org
· Delegate
2013 (Luxembourg/LU) 2nd International Systems Biomedicine Symposium
Organized by: Univ. of Luxembourg, http://www.uni.lu
· Delegate
2012 (Pernambuco/BR) Brazilian Northeastern Genetics Meeting
Organized by: UNIVASF, http://www.engene.univasf.edu.br/
· Tutor: Mini-course: web-resources applied to the study of biological systems
2012 (Brasilia/BR) Brazilian-German Frontiers in Science and Technology
Organized by: CAPES and AvH Foundation
http://www.humboldt-foundation.de/web/bragfost-2012.html
· Delegate
2012 (São Paulo/BR) 8th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting)
Organized by: AB3C, http://www.x-meeting.com
· Speaker: Text Mining for Biological Knowledge Extraction.
· Covre RA, Lopes KP, Monteiro RA, Brusamarello LCC, Souza EM, Pedrosa FO, Barbosa-Silva A (2012) Wedring: a pipeline for analysis of differential gene expression in RNA-Seq. In: Proceedings of the 8th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Campinas – SP, Brazil.
· Lopes KP, Covre RA, Brusamarello LCC, Wassem R, Souza EM, Pedrosa FO, Barbosa-Silva A (2012) Identification of rice alternatively spliced and new transcripts in response to diazotrophic inoculation using RNA-Seq data. In: Proceedings of the 8th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Campinas – SP, Brazil.
· Lopes KP, Covre RA, Brusamarello LCC, Wassem R, Souza EM, Pedrosa FO, Barbosa-Silva A (2012) RNA-Seq based identification of alternative splicing in transcription start sites of rice mRNAs. In: Proceedings of the 8th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Campinas – SP, Brazil.
· Stussi F, Guedes RLM, Barbosa-Silva A, Ortega JM (2012) Depicting the origin of sumoylation network in Arabdopsis thaliana with text-mining and orthologue clustering tools. In: Proceedings of the 8th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Campinas – SP, Brazil.
· Barbosa-Silva, A. (2010) Integrating biological concepts into protein-protein interactions using text mining. In: Proceedings of the Brasil-Deutschland Systems Biology Meeting (SB-Meeting). Ouro Preto – MG, Brasil.
2011 (Santa Catarina/BR) 7th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting)
Organized by: AB3C, http://www.x-meeting.com
· Chair: Full paper presentation session.
· Stussi, F., Guedes, R., Velloso, H., Donnard, E., Ribeiro, H., Fernandes, G., Barbosa-Silva, A., Andrade-Navarro, M., Ortega, J.M. (2011) Depicting the origin of drought response in Arabidopsis thaliana with text-mining and orthologue clustering tools. In: Proceedings of the 6th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Florianopolis – SC, Brazil.
· Barbosa-Silva, A., Fontaine., J.F., Donnard, E., Stussi, F., Ortega, J.M., Andrade-Navarro, M. (2011) Efficient network curation using the text-mining tool PESCADOR. In: Proceedings of the 6th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Florianopolis – SC, Brazil.
· Lopes, K.P., Covre, R.A., Brusamarello-Santos, L.C.C., Wassem, R., Souza, E.M., Pedrosa, F.O., Barbosa-Silva, A. (2011) Initial mapping of rice cDNA short-sequences created by RNA-Seq. In: Proceedings of the 6th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Florianopolis – SC, Brazil.
· Covre, R.A., Lopes, K.P., Brusamarello-Santos, L.C.C., Wassem, R., Souza, E.M., Pedrosa, F.O., Barbosa-Silva, A. (2011) Pipeline for analysis of RNA-Seq short-sequences using open source softwares. In: Proceedings of the 6th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Florianopolis – SC, Brazil.
2010 Brasil-Deutschland Systems Biology Meeting (SB- Meeting)
· Speaker: Learning from homologs.
· Chair: Best-posters oral presentation.
· Barbosa-Silva, A. (2010) Integrating biological concepts into protein-protein interactions using text mining. In: Proceedings of the Brasil-Deutschland Systems Biology Meeting (SB-Meeting). Ouro Preto – MG, Brasil.
Organized by UFMG and DKFZ: http://www.sb-meeting.com
2009 5th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting)
· Chair: Lecture 4: Comparative Metagenomics. Peer Bork – EMBL Heidelberg.
· Speaker: PESCADOR: concepts associated to co-occurrences relationships.
· Guedes, R.L.M., Fernandes, G.D.R., Coelho-Junior, O.S., Ribeiro, H.A.L., Barbosa-Silva, A., Ortega, J.M. (2009) Survey of phosphate kinases in 17.65 million metagenomics sequences using clusters of homologues built with SeedServer. In: Proceedings of the 5th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Angra dos Reis – RJ, Brasil.
· Donnard, E., Barbosa-Silva, A., Ortega, J.M. (2009) In pursuit of a KEGG-like pathway for the preimplantation development using the text mining tool LAITOR to reveal biointeractions. In: Proceedings of the 5th International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Angra dos Reis – RJ, Brasil.
Organized by AB3C: http://www.x-meeting.com
2009 I Pernambuco Bioinformatics Workshop
· Speaker
2009 6th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics – CIBB
· Chair
Organized by Univ. of Genova (Italy): http://cibb09.disi.unige.it/
2009 2nd German National Genome Research Network (NGFN) Meeting
· Fontaine, J.-F., Barbosa-Silva, A.; Spruth, E., Priller, J., Andrade-Navarro, M.A. Hypothesis generation for neurodegenerative diseases pathogenesis using text-mining
Organized by BMBF: http://www.bmbf.de/
2008 1st German National Genome Research Network (NGFN) Meeting
· Fontaine, J.-F., Barbosa-Silva, A.; Andrade-Navarro, M.A. Ranking the biomedical Literature for optimized experimental designs
Organized by BMBF: http://www.bmbf.de/
2007 53° Brazilian Congress of Genetics
· Barbosa-Silva, A.; Satagopam, V.P.; Schneider, R.; Ortega, J.M. Clustering of inparalog and co-ortholog proteins in clusters founded by single seeds.
Organized by SBG: http://www.sbg.org.br
2007 I Workshop of the UFMG’s Bioinformatics PhD Course.
· Speaker: Mineração de texto, agrupamento de seqüências e integração de dados para contrução de uma base de dados on-line de proteínas de defesa em plantas.
Organized by Bioinformática - UFMG: http://www.bioinfo.icb.ufmg.br
2005 I International Workshop on Genomic Databases
· Cestari, I.S.; Barbosa-Silva, A.; Araya, M.I.R. Functional Analyses of Trypanosomatids Hypothetical Proteins.
Organized by FIOCRUZ: http://www.biowebdb.org/iwgd05/
2005 1st International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting)
· Committee member;
· Barbosa-Silva, A., Mudado, M., Ortega, J. M. (2005). Plant Defense Mechanisms Database (PDM): Building and Evaluation. In: Proceedings of the 1st International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Caxambu – MG, Brasil.
· Casanova, F. M., Andrade, P. P., Kido, E. A., Cavalcanti, E. S., Rayol, C. A., Barbosa, A. (2005). Patterns of gene expression from Leishmania ProGeNE cDNA libraries. In: Proceedings of the 1st International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Caxambu – MG, Brasil.
· Rates, B. Barbosa-Silva, A., Nascimento, D. G., Santos, D. M., Braga, T. V., Dutra, A. A. A., Lima, M. E., Pimenta, A. M. C. (2005). Machine learning-based clustering analysis of venom 2D-LC/MS data to infer phylogenetic relationships in scorpions from the Buthidae family. In: Proceedings of the 1st International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X- Meeting). Caxambu - MG, Brasil.
· Barbosa, D. V. C., Faria-Campos, A. C., Barbosa, A., Ortega, J. M. (2005). Identification of the divergent genes in group of paralogs from microorganisms with complete genome. In: Proceedings of the 1st International Conference of the Brazilian Association of Bioinformatics and Computational Biology (X-Meeting). Caxambu - MG, Brasil.
Organized by AB3C: http://www.x-meeting.com
2005 VIII ICB Research Meeting / III Annual Meeting for Research in Biochemistry and Immunology (ENAPEBI)
Organized by ICB/UFMG: http://www.icb.ufmg.br
2005 51° Brazilian Congress of Genetics
· Barbosa, A., Mudado, M. A., Ortega, J. M. (2005) PDM, A Plant Defense Mechanism Database Suitable For Automatic Annotation and Classification. In: Anais do 51° Congresso Brasileiro de Genética. Águas de Lindóia – SP, Brasil.
Organized by SBG: http://www.sbg.org.br
2004 II International Conference on Bioinformatics and Computational Biology
· Mudado, M. A., Pinto, S. A. P., Barbosa, A. S., et al. (2004). A Picture of the Sampling of Gene Expression In Model Metazoa Using EST And KOG Proteins. In: II International Conference on Bioinformatics and Computational Biology. Angra dos Reis – RJ, Brasil.
· Barbosa, A., Benko-Iseppon, A. M. (2004). In silico screening of tomato disease resistance pathway in sugarcane transcriptome. In: II ICOBICOBI - International Conference on Bioinformatics and Computational Biology. Angra dos Reis – RJ, Brasil.
Organized by AB3C: http://www.ab3c.org
2003 III Brazilian Biosafety Conference and III Latin-American Symposia on GMO Products .
· Committee member;
Organized by the Brazilian Biosafety Association: http://www.anbio.org.br
2003 49° Brazilian Congress of Genetics
· Barbosa, A., Morais, D. A. L., Benko-Iseppon, A. M. (2003). Data mining approach used to characterize putative disease resistance gene Pti1 on sugarcane transcriptome. In: Anais do 49° Congresso Brasileiro de Genética. Águas de Lindóia – SP, Brasil.
Organized by SBG: http://www.sbg.org.br
2002 XXXV Phytopathology Brazilian Congress
· Barbosa, A., Morais, D. A. L., Benko-Iseppon, A. M. (2002). Sugarcane ESTs Data Mining revels homolog sequences to Lr10 gene from wheat. In: Anais do XXXV Congresso Brasileiro de Fitopatologia. Recife – PE, Brasil.
Organized by Brazilian Society of Phytopathology: http://www.sbfito.com.br/
2002 48° Brazilian Genetics Congress
· Barbosa, A., Morais, D. A. L., Benko-Iseppon, A. M. (2003). In silico screening of sugarcane homolog sequences to tomato Pto R-gene. In: Proceedings of the 48th Brazilian Congress of Genetics. Águas de Lindóia – SP, Brasil.
Organized by SBG: http://www.sbg.org.br
2002 I Brazilian Congress of University Extension.
Organized by the Forum of the pro-rectories for extension of the Brazilian public universities: http://www.renex.org.br/
2001 IX UFPE’s Scientific Initiation Conference
· Barbosa, A., Morais, D. A. L., Benko-Iseppon, A. M. (2001). Análise comparativa de genes de resistência a bactéria Pseudomonas syringae de Arabidopsis thaliana no genoma da cana-de-açúcar. In: Anais do XI Congresso de Iniciação Científica da UFPE. Recife – PE, Brasil.
Organized by UFPE: http://www.ufpe.br
2001 Workshop of the technology-based enterprises of the Pernambuco state.
Organized by FACEPE: http://www.facepe.br
2001 Parasitic Proteomics Workshop
Organized by FACEPE: http://www.facepe.br
2001 Workshop: Research, venture-capital and the Brazilian biotechnology industries, the experience of FK-Biotecnologia S.A.
Organized by FACEPE: http://www.facepe.br
2001 Workshop: Pernambuco State Biotechnology Program
Organized by FACEPE: http://www.facepe.br
2001 V UPE’s Scientific Initiation Workshop
Organized by FACEPE: http://www.facepe.br
2001 Workshop: Technologic opportunities of Genomics
Organized by FACEPE: http://www.facepe.br
2000 Building the pedagogic Project of the UFPE
Organized by UFPE: http://www.ufpe.br
2000 VIII UFPE’s Scientific Initiation Conference
Organized by UFPE: http://www.ufpe.br
2000 X EREB-NE: National Meeting of the Brazilian North-eastern Students
Organized by UFPI: http://www.ufpi.br
Contact adriano[dot]bioinfo[at]gmail[dot]com to get more information.