Workshop details

The vast amount of biological information collected over the last decades allow us to model without precedents how biological systems work. In this workshop we will explore the main concepts of Systems Biology and learn how to use individual entities to create a holistic snapshot of a biological system.

Learning objectives

• Identify the elements of a biological system;

• Understand the molecular foundations of links among biological components;

• Explore protein-protein networks;

• Identify the sources of complexity in biological systems;

• Explore gene expression databases such as Array Express and Expression Atlas;

• Explore how networks can be represented and analyzed.

Syllabus

• Components of biological systems;

• Links between systems biology components;

• Chemical nature of biological links;

• Molecular interactions;

• Allosteric regulation;

• Conformational change;

• Key properties of chemical reactions;

• Principles of systems biology;

• Functional states;

• Protein-protein networks;

• Link to networks;

• Complexity of biological systems;

• Gene expression complexity;

• Array Express & Gene Expression Atlas;

• Metabolic Pathways Data;

• Genomic Information;

• Gene information;

• Protein-protein interaction networks

• Network construction;

• Two-hybrid screens and validation;

• Network analysis and modelling;

• Network characteristics;

• Subnetwork motifs;

• Extension of protein-protein networks;

• Visualization of PPIs;

• String Database;

Format

• Zoom live webinar: 1h live webinar with pre-recorded presentation split in two sessions of 30min each with a break of 5min between them. Attendees are welcome to join asynchronous live group discussion (Q&A) with the speaker on Discord during and after the scheduled session.

• General discussion session: 1h Q&A recurrent pre-dated session booked for attendees of multiple slots of this workshop.

• Recorded presentation: Attendees registering using a Google e-mail account, will have private access to the recorded webinars.

• Certificate: all attendees checking-in and out of both 30min sessions will be entitled to receive a certificate of participation (PDF/PNG) that can be shared on your social media with credentials (QR-code) that can be verified on our website, with an option (extra fee) to register as a NFT asset with an unique address on the Ethereum blockchain.